Korgel Group :: Mike Rasch

Michael Rasch

EDUCATION

B.S., Chemical Engineering, University of Delaware, 2006

Ph.D., Chemical Engineering, University of Texas, 2012

RESEARCH INTERESTS

We are interested in developing nanomaterials to help study and manipulate biological systems. Our group synthesizes nanoparticle contrast agents for optical and magnetic resonance imaging, and we are now working on targeting these agents to unique cell receptors for better characterization of diseases such as cancer. In addition, we are focused on coupling these nanocrystals to drug-carrying agents, such as lipid vesicles and bacteriophages, to yield new hybrid materials providing enhanced control over in vivo drug distribution. Our group also synthesizes semiconductor nanowires, and we are beginning to grow nerve cells on biomolecule-passivated nanowire substrates. We intend to study the electrical interactions between nanowires and individual nerve cells in an effort to read the cell's electrical signals.

SELECTED PUBLICATIONS

Rasch, Michael R.; Bosoy, Christian; Yu, Yixuan; Korgel, Brian A., Chains, Sheets, and Droplets: Assemblies of Hydrophobic Gold Nanocrystals with Saturated Phosphatidylcholine Lipid and Squalene. Langmuir (2012), 28 (43), 15160-15167. [link]

Rasch, Michael R.; Yu, Yixuan; Bosoy, Christian; Goodfellow, Brian W.; Korgel, Brian A., Chloroform-Enhanced Incorporation of Hydrophobic Gold Nanocrystals into Dioleoylphosphatidylcholine (DOPC) Vesicle Membranes. Langmuir (2012), 28 (36), 12971-12981. [link]

Hessel, Colin M.; Reid, Dariya; Panthani, Matthew G.; Rasch, Michael R.; Goodfellow, Brian W.; Wei, Junwei; Fujii, Hiromasa; Akhavan, Vahid; Korgel, Brian A., Synthesis of Ligand-Stabilized Silicon Nanocrystals with Size-Dependent Photoluminescence Spanning Visible to Near-Infrared Wavelengths. Chemistry of Materials (2012), 24 (2), 393-401. [link]

Hessel, Colin M.; Pattani, Varun P.; Rasch, Michael; Panthani, Matthew G.; Koo, Bonil; Tunnell, James W.; Korgel, Brian A., Copper Selenide Nanocrystals for Photothermal Therapy. Nano Letters (2011), 11(6), 2560-2566. [link]

Smith, Damon A.; Holmberg, Vincent C.; Rasch, Michael R.; Korgel, Brian A., Optical Properties of Solvent-Dispersed and Polymer-Embedded Germanium Nanowires. Journal of Physical Chemistry C (2010), 114(49), 20983-20989. [link]

Hessel, Colin M.; Rasch, Michael R.; Hueso, Jose L.; Goodfellow, Brian W.; Akhavan, Vahid A.; Puvanakrishnan, Priyaveena; Tunnel, James W.; Korgel, Brian A., Alkyl Passivation and Amphiphilic Polymer Coating of Silicon Nanocrystals for Diagnostic Imaging. Small (2010), 6(18), 2026-2034. [link]

Rasch, Michael R.; Rossinyon, Emma; Hueso, Jose L.; Goodfellow, Brian W.; Arbiol, Jordi; Korgel, Brian A., Hydrophobic Gold Nanoparticle Self-Assembly with Phosphatidylcholine Lipid: Membrane-Loaded and Janus Vesicles. Nano Letters (2010), ASAP. [link]

Holmberg, Vincent C.; Rasch, Michael R.; Korgel, Brian A., PEGylation of Carboxylic Acid-Functionalized Germanium Nanowires. Langmuir (2010), 26(17), 14241-14246. [link]

Rasch, Michael R.; Sokolov, Konstantin V.; Korgel, Brian A., Limitations on the Optical Tunability of Small Diameter Gold Nanoshells. Langmuir (2009), 25(19), 11777-11785. [link]

Smith, D. K.; Rasch, M. R.; and Korgel, B. A., Novel nanocrystals as a platinum-delivery vehicle for chemotherapy. Nanomedicine (2007), 2, 943-949.

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